Deaths from hydrocodone, oxycodone and other opioid pain medications have quadrupled since 1999 increasing from 4,030 deaths to 16,651 deaths in 2010. During the amount of opiate pain medications prescribed has quadrupled as well. Pharmaceutical companies and some pain management physicians claim that only a few patients are susceptible to death from overdose and believe that a screening tool can differentiate patients at low risk for overdose from high risk patients. A recent article in the Journal of the American Medical Association (JAMA) shows that opioid dependence is more common than believed and affects approximately one-third (1/3) of patients with chronic pain. Simply put, opioid pain relievers, and especially oxycodone and hydrocodone, are dangerous drugs.