Acetaminophen 500 mg instead of aspirin 81 mg was distributed in a lot of Rugby-label enteric coated aspirin and the manufacturer Advanced Pharmaceutical Inc of Holtsville, NY has issued a voluntary recall after receiving a complaint about the mislabeled drug. Lot 13A026 with an expiration date of January 2015 was distributed nationwide. This OTC product is indicated for temporary relief of minor aches and pains and is packaged in bottles of 120 tablets with NDC 0536-3086-41 and UPC 0536-3086-419. The recall was ordered on June 17 to prevent consumers from inadvertently taking acetaminophen 500 mg that can cause severe liver damage if combined with other acetaminophen products, alcoholic drinks or liver disease.
Treatment of recent lacunar stroke with aspirin alone compared with aspirin and Plavix shows that aspirin is as effective as using both together. More importantly, aspirin alone caused fewer major hemorrhages and death. A recent study in the New England Journal of Medicine investigate treatment of patients who suffered acute lacunar strokes. These brain infarcts result from occlusion of one of the arteries that penetrate into the deep brain structures and can result in typical symptoms as well as ataxia (incoordinated muscular movements), dysarthria (difficulty saying words) and clumsiness of the hand especially when writing.
The Journal of the National Cancer Institute reported that the daily use of aspirin helps prevent death from cancers. Dr. Eric Jacobs did the study to further investigate a report of an estimated 37% reduction in deaths among people using aspirin for 5 years of more. Data from 110,139 elderly individuals participated in the study and were followed for 11 years. There was an overall mortality reduction of 16%, with a reduction in mortality of 40% for gastrointestinal malignancies and about a 12% decrease for all others.